Prothrombin time
About
Prothrombin time is a quick and sensitive test used to assess blood coagulation, i.e., the blood’s ability to clot. The test measures the time it takes for a clot to form in a blood sample (plasma). The result can be expressed as a percentage or ratio (>0.70) or as an INR value (International Normalized Ratio) to standardize results across different laboratories.
Certain medications aim to reduce the speed of blood clotting, which can lead to a lower percentage result (ratio) or a higher INR value. The recommended range for monitoring oral anticoagulant therapy is an INR between 2.0 and 3.5.
Candidate
You should have this test if you want to check your blood clotting function, if you have known inherited or acquired clotting disorders, if you are taking or planning to take oral contraceptives, if you are preparing for surgery, have liver disease, experience subcutaneous bleeding (hematomas), or especially if you are using anticoagulant medications (e.g., warfarin).
Preparation
For this test, you must fast, as eating immediately before blood draw can cause lipemia, which may interfere with the measurement of prothrombin time. NOTE for individuals on oral anticoagulant therapy: DO NOT TAKE your medication immediately before the blood draw!
Treatment
To determine prothrombin time, blood is drawn from a vein.
Result
The results are available the same day.
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