Stem Cell Therapy in Orthopedics

About

Stem cell therapy is one of the most advanced forms of regenerative medicine in orthopedics. It uses the patient’s own stem cells – typically harvested from fat tissue or bone marrow – to promote the repair of damaged joints, tendons, ligaments, cartilage, and even bone. In orthopedic practice, it is applied in early to moderate stages of osteoarthritis, partial tendon and ligament tears, joint pain, and chronic inflammation. Stem cells stimulate natural healing, reduce pain, and improve function – all without the need for surgery.

Candidate

This therapy is ideal for patients with chronic joint pain (knee, hip, shoulder), early to moderate osteoarthritis, or partial tendon/ligament injuries that haven’t responded to standard treatments. It is especially recommended for those wishing to delay or avoid surgery while the joint structure is still relatively preserved. It is not suitable for patients with active infections, cancer, blood disorders, or during pregnancy.

Preparation

Before treatment, basic lab tests and a clinical evaluation are required. Alcohol and heavy meals should be avoided the day before, and the patient usually needs to arrive fasting. Your doctor may recommend stopping certain medications. The harvesting of stem cells is performed under local or short general anesthesia, depending on the method.

Treatment

Stem cells are extracted either through liposuction (from abdominal fat) or bone marrow aspiration (from the pelvic bone). The material is processed to isolate and concentrate the stem cells, which are then injected into the damaged area – such as a joint, tendon, or ligament – usually under ultrasound guidance. The procedure takes 1–2 hours and is minimally invasive, with patients typically discharged the same day.

Result

Results are not immediate. Improvement usually begins within 4 to 8 weeks, with continued progress over 6 months. Patients often experience less pain, better mobility, and overall improved joint function. In many cases, disease progression slows significantly, potentially postponing surgery for years. Results can last a long time, depending on patient health and lifestyle.

Precautions

After the procedure, rest is advised for a few days, followed by gradual activity. Some swelling, tenderness, or bruising may occur but should resolve within a few days. Avoid anti-inflammatory medications for at least 2 weeks. Physical therapy is recommended to support recovery. Regular follow-up is important to track progress.

F.A.Q.

What are stem cells and how do they work in orthopedics?

They are cells capable of regenerating tissue – they promote healing of damaged joints, tendons, and ligaments.

Where are the stem cells taken from?

Usually from fat tissue (via liposuction) or bone marrow from the pelvic bone.

Is the procedure painful?

The procedure is done under anesthesia, and only mild discomfort may occur afterward.

When will I notice improvement?

Improvement is typically felt after 4 to 8 weeks.

How long do results last?

Results may last from one year to several years, depending on the condition.

Are there any risks or side effects?

Risks are minimal, as the cells come from your own body – mild swelling or pain is possible.

Can the therapy be repeated?

Typically once per year, depending on the doctor’s recommendation and clinical response.

Can it replace surgery?

In many cases, it can delay or even eliminate the need for surgery

Is there an age limit for treatment?

Not strictly, but better outcomes are seen in younger patients or those with preserved joint structure.

Is it approved and safe?

Yes, it is used worldwide and performed according to medical safety standards.

Ivana, Patient Coordinator

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Ivana, ZagrebMed patient coordinator